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Lewin S Essential Genes

Lewin s Essential GENES PDF

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Author: Jocelyn E. Krebs
Publisher: Jones & Bartlett Publishers
ISBN: 1284173135
Size: 50.55 MB
Format: PDF, ePub, Docs
Category : Science
Languages : en
Pages : 1044
View: 6544

Book Description: Extensively reorganized and revised with the latest data from this rapidly changing field, Lewin's Essential GENES, Fourth Edition, provides students with a comprehensive overview of molecular biology and molecular genetics. The authors took care to carefully modify the chapter order in an effort to provide a more clear and student-friendly presentation of course material. Chapter material has been updated throughout, including a completely revised chapter on regulatory RNA, to keep pace with this advancing field. The Third Editions exceptional pedagogy enhances student learning and helps readers understand and retain key material like never before. Concept and Reasoning Checks at the end of each chapter section, End-of-Chapter Questions and Further Readings sections, as well as several categories of special topics boxes, expand and reinforce important concepts.


Homology Genes And Evolutionary Innovation

Homology  Genes  and Evolutionary Innovation PDF

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Author: Günter P. Wagner
Publisher: Princeton University Press
ISBN: 0691180679
Size: 68.61 MB
Format: PDF, Mobi
Category : Science
Languages : en
Pages : 496
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Book Description: A major synthesis of homology, written by a top researcher in the field Homology—a similar trait shared by different species and derived from common ancestry, such as a seal's fin and a bird’s wing—is one of the most fundamental yet challenging concepts in evolutionary biology. This groundbreaking book provides the first mechanistically based theory of what homology is and how it arises in evolution. Günter Wagner, one of the preeminent researchers in the field, argues that homology, or character identity, can be explained through the historical continuity of character identity networks—that is, the gene regulatory networks that enable differential gene expression. He shows how character identity is independent of the form and function of the character itself because the same network can activate different effector genes and thus control the development of different shapes, sizes, and qualities of the character. Demonstrating how this theoretical model can provide a foundation for understanding the evolutionary origin of novel characters, Wagner applies it to the origin and evolution of specific systems, such as cell types; skin, hair, and feathers; limbs and digits; and flowers. The first major synthesis of homology to be published in decades, Homology, Genes, and Evolutionary Innovation reveals how a mechanistically based theory can serve as a unifying concept for any branch of science concerned with the structure and development of organisms, and how it can help explain major transitions in evolution and broad patterns of biological diversity.


Theories Of Population Variation In Genes And Genomes

Theories of Population Variation in Genes and Genomes PDF

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Author: Freddy Bugge Christiansen
Publisher: Princeton University Press
ISBN: 0691165890
Size: 61.60 MB
Format: PDF, Mobi
Category : Science
Languages : en
Pages : 432
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Book Description: This textbook provides an authoritative introduction to both classical and coalescent approaches to population genetics. Written for graduate students and advanced undergraduates by one of the world's leading authorities in the field, the book focuses on the theoretical background of population genetics, while emphasizing the close interplay between theory and empiricism. Traditional topics such as genetic and phenotypic variation, mutation, migration, and linkage are covered and advanced by contemporary coalescent theory, which describes the genealogy of genes in a population, ultimately connecting them to a single common ancestor. Effects of selection, particularly genomic effects, are discussed with reference to molecular genetic variation. The book is designed for students of population genetics, bioinformatics, evolutionary biology, molecular evolution, and theoretical biology--as well as biologists, molecular biologists, breeders, biomathematicians, and biostatisticians. Contains up-to-date treatment of key areas in classical and modern theoretical population genetics Provides in-depth coverage of coalescent theory Discusses genomic effects of selection Gives examples from empirical population genetics Incorporates figures, diagrams, and boxed features throughout Includes end-of-chapter exercises Speaks to a wide range of students in biology, bioinformatics, and biostatistics


Genes Brain Function And Behavior

Genes  Brain Function  and Behavior PDF

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Author: Douglas Wahlsten
Publisher: Academic Press
ISBN: 0128128321
Size: 17.74 MB
Format: PDF, Mobi
Category : Science
Languages : en
Pages : 450
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Book Description: Genes, Brain Function, and Behavior offers a concise description of the nervous system that processes sensory input and initiates motor movements. It reviews how behaviors are defined and measured, and how experts decide when a behavior is perturbed and in need of treatment. Behavioral disorders that are clearly related to a defect in a specific gene are reviewed, and the challenges of understanding complex traits such as intelligence, autism and schizophrenia that involve numerous genes and environmental factors are explored. New methods of altering genes offer hope for treating or even preventing difficulties that arise in our genes. This book explains what genes are, what they do in the nervous system, and how this impacts both brain function and behavior. Presents essential background, facts, and terminology about genes, brain function, and behavior Builds clear explanations on this solid foundation while minimizing technical jargon Explores in depth several single-gene and chromosomal neurological disorders Derives lessons from these clear examples and highlights key lessons in boxes Examines the intricacies of complex traits that involve multiple genetic and environmental factors by applying lessons from simpler disorders Explains diagnosis and definition Includes a companion website with Powerpoint slides and images for each chapter for instructors and links to resources


How Genes Influence Behavior 2e

How Genes Influence Behavior 2e PDF

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Author: Jonathan Flint
Publisher:
ISBN: 0198716877
Size: 21.45 MB
Format: PDF, ePub, Docs
Category :
Languages : en
Pages : 392
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Book Description: How Genes Influence Behavior takes a personal and lively approach to the study of behavioral genetics, providing an up-to-date and accessible introduction to a variety of approaches and their application to a wide range of disorders, and modeling a critical approach to both methods andresults.This second edition includes additional biology content to help students understand the biological foundations of the field, while maintaining an appropriate focus on the main issues of relevance to psychology students; updates coverage of genomic technologies and their applications; and covers awider range of disorders, including autism spectrum disorder, eating disorders, and intellectual disability. A new final chapter guides students through a range of quantitative approaches using worked examples that relate directly to cases and examples used earlier in the text, and addresses currentissues arising from debates around reproducibility.The online resources that accompany this book include:For students* Multiple choice questions for students to check their threshold knowledge* Data sets for students to manipulate, so that they can apply what they have learnedFor lecturers* Figures and tables from the book, ready to download


Genes And Human Nature

Genes and Human Nature PDF

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Author: Hussein A. Amin
Publisher: AuthorHouse
ISBN: 1425926517
Size: 35.48 MB
Format: PDF, Mobi
Category : Body, Mind & Spirit
Languages : en
Pages : 257
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Book Description: Mankind is defined not as the animals that have souls, but as the animals that can INVENT ideas, and then TALK about them, (inventiveness and language). Signs of these two momentous abilities are documented to have SUDDENLY started only about 30,000 years ago. The G-SAT Theory, detailed in this book, offers a SCIENTIFIC frame, for a master-planned, purely physical process, that initiated Mankind. DNA is NOT synonymous with 'GENES'. DNA is the ink and paper on which the encoded messages of the genes get recorded. Every year, we come closer to deciphering how these messages work. With this rapidly progressing scientific discipline, we are getting closer, by the day, to scientifically proving my pre-determined-encoded theory.


Cortical Deficits In Schizophrenia

Cortical Deficits in Schizophrenia PDF

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Author: Patricio O'Donnell
Publisher: Springer Science & Business Media
ISBN: 0387743510
Size: 77.97 MB
Format: PDF, Mobi
Category : Medical
Languages : en
Pages : 239
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Book Description: This hugely important text aims to illuminate one of the most difficult areas of study in psychiatric medicine – the basis for schizophrenia in human DNA. The genetics of schizophrenia have been elusive for decades. Lately, however, a complex set of genes and gene variations that confer predisposition to schizophrenia have been identified. The challenge is to understand the biology of the genes and find out how they exert their influence. Here is all the latest research.


Genes

Genes PDF

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Author: Jonathan Slack
Publisher: Oxford University Press, USA
ISBN: 019967650X
Size: 76.14 MB
Format: PDF
Category : Science
Languages : en
Pages : 120
View: 1559

Book Description: Explores the discovery, nature, and role of genes in evolution and development.


Genetics

Genetics PDF

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Author: Daniel L. Hartl
Publisher: Jones & Bartlett Learning
ISBN: 9780763758684
Size: 76.17 MB
Format: PDF, ePub, Docs
Category : Science
Languages : en
Pages : 763
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Book Description: This handbook covers all dimensions of breast cancer prevention, diagnosis, and treatment for the non-oncologist. A special emphasis is placed on the long term survivor.


Unzipped Genes

Unzipped Genes PDF

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Author: Martine Aliana Rothblatt
Publisher: Temple University Press
ISBN: 9781566395540
Size: 77.11 MB
Format: PDF, Kindle
Category : Medical
Languages : en
Pages : 201
View: 1561

Book Description: How will we handle baby-making and pregnancy in the next 5, 25, and 75 years? New reproductive technology, genetic screening, and DNA-mapping have changed the 20th-century rules. In this revolutionary manifesto, Martine Rothblatt proposes a code of ethics to guide childbirth decisions in the brave new world of biotechnology.The trigger for Unzipped Genesis the Human Genome Project, a multibillion dollar effort to unlock the secrets of the human genetic code. This new "genomic" knowledge can be used for tremendous good, such as curing disease, or unprecedented harm, such as the kinds of master race eugenics already visible in Asia, where social pressures force families to choose to abort female fetuses. Without a bioethics of birth, we risk creating a new kind of racism, which Rothblatt calls "genism," based on officially sanctioned genetic characteristics. Unregulated genetic decision-making can open the door to invasion of privacy, efforts to eliminate certain kinds of people from the gene pool, or government or corporate efforts to gain control of the human genome.Rothblatt bases her bioethics of birth on four principles designed to empower the beneficial potential of genomics without unleashing genism. First, we must agree that the human genome belongs indivisibly to us all. Second, we must allow each person an unfettered right to intentionally create in his or her children new versions of the genome without limitations on its genetic characteristics. Third, we must insist that society has a right to help prevent unwanted pregnancies. And finally, we must ensure that genetically influenced characteristics -- from skin tone to predispositions to disease, from sexual orientation to various mental inclinations -- will not be the basis of discrimination of any kind.Writing concretely and persuasively, Rothblatt explains the biotechnology of the Human Genome Project in terms we all can understand. Not limiting her bioethics to the realm of abstraction, she maintains that her new bioethics of birth will lead to the end of abortion and unwanted pregnancy and the creation of a world in which people can achieve a greater solidarity with one another. Author note: Martine Rothblatt is an international high-tech lawyer and speaker on bioethics in Washington, D.C. She is also the Chairperson of the Bioethics Subcommittee of the International Bar Association and the author of The Apartheid of Sex.